Bagnaia's teammate Enea Bastianini is the latest rider to come unstuck after falling at turn five.
Bagnaia jumps up to third behind Bezzecchi and Quartararo.
Mistake from Quartararo on his latest lap as he runs wide at turn 13.
Joan Mir is again quicker than Marc Marquez so far as four tenths separates the two Repsol riders.
Most of the grid is currently in pit lane as Bezzecchi remains fastest for Mooney VR46 Ducati.
A name to watch out for when it comes to surprise winners in today's Sprint, Alex Marquez is again showing strong pace. The Gresini rider is P3 at the moment.
it was Miller who Marini clipped before crashing at turn ten.
Bezzecchi moves to the top of the leaderboard with a time of 1:38.577s.
Quartararo is currently fastest from Bagnaia as race runs are the focus in P3.
Marini looked unstable as he got back to his feet.
Luca Marini has crashed on his out lap after contact with one of the two factory KTM riders.
We're underway with P3 at Portimao.
Jack Miller was fastest for KTM in P2 while Maverick Vinales and Francesco Bagnaia rounded out the top three.
Before that we have Practice 3 which gets underway in just over five minutes time, quickly followed by qualifying.
Good morning and welcome to Sprint race day, the first of its kind in MotoGP, at Portimao
Miller ends day-one in Portimao top!
Marc Marquez has crashed and his session is over.
Stunning final sector from Miller as he goes top out of nowhere!
WOW! Vinales goes fastest for Aprilia!!
Bagnaia has ran into trouble and is at the side of the track with his Ducati. It seems as though the world champion has ran out of fuel.
Bagnaia with a new lap record as he goes close to two tenths clear of Martin.
Wow, Martin sets a sub 1m 38s lap, which is the first time such a lap time has been set in an official session at Portimao.
Luca Marini has crashed in sector four whilst on a lap that could have seen him go top.
Marc Marquez has positioned himself directly behind Quartararo for the final few laps.